Screen 44 genes for the most common hereditary mutations that can cause cancer
The Hereditary Cancer Testing Kit helps our patients learn whether they’re predisposed to developing one or more cancers.
See All BenefitsGenes contain the information your body uses to grow and function. You have 2 copies of each gene, with 1 copy inherited from each parent. Sometimes, particular mutations, or changes, to genes can increase the risk of developing cancer. These mutations may be a sporadic, one-time change that occur during your life. Or, the mutations may be inherited from your parents. When a certain type of cancer seems to be common in a family, doctors may be able to identify the specific genetic change causing the increased risk. These types of genetic changes are called “hereditary cancers” or “inherited cancer syndromes.” Specific laboratory tests can identify these changes before cancer even develops.
An example of inherited genetic changes that may increase a person’s risk of developing cancer, and at an earlier age than other people, are BRCA1 and BRCA2 mutations. These mutations increase the risk of breast cancer and pancreatic cancer in both men and women, the risk of ovarian cancer in women, and the risk of prostate cancer in men.
Knowledge of an increased genetic risk enables you to work with your healthcare provider to create a personalized plan to prevent or detect cancer at an earlier and more treatable stage. It is typical to see a recurring pattern of cancer across two to three generations, with multiple individuals diagnosed with the same type of cancer(s).
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Benefits of our Hereditary Cancer Testing include:
World Class Genetic Hereditary Cancer Testing — Trusted by more than 232,000 satisfied clients to date.
Who needs this test?
Knowing your risk lets you to take necessary action
This might include:
Earlier and more frequent screenings:
For example, if you have an increased risk for breast cancer, your healthcare provider might recommend mammograms at an earlier age.
Preventative measures:
Your healthcare provider may suggest preventive measures, such as certain medications that can reduce your cancer risk.
Proactive care for your family:
As hereditary cancer runs in families, your results can help your loved ones understand their hereditary risk, too.
Life saving potential:
Preventative surgery, like mastectomy, can significantly reduce your risk—and may even save your life.
Treatment benefits:
Genetic information can qualify you for treatments not publicly available through participation in clinical trials.
How it works
We’re driven by our commitment to deliver exceptional experiences to our customers. We value our strong customer relationships and are defined by them.
Step 1
Do you qualify?
Fill in our intake questionnaire, online or via phone. We will assess your request and share it with a Telemedicine Physician to conduct a consult with you. If the physician approves your request, we will send you a kit in the mail, at no charge.
Step 2
Receive Your Test Kit
Once you receive your kit, follow the instructions inside and administer the test on yourself. You can also visit your local health care provider and have them conduct it for you.
Step 3
Send Kit To Lab
Place your sample back in the kit. Make sure the pre-paid sticker is placed outside of the kit, and drop it off in your mailbox for pickup.
Step 4
Processing & Report
Get results sent to you and your physician via email as well as a hard copy sent to your house.
Privacy
How is my privacy protected?
To prevent unauthorized access or disclosure, to maintain data accuracy, and to ensure the appropriate use of information, we have incorporated a number of physical, technical, and administrative security measures.
Your personal information and privacy is always assured in accordance with current technological and industry standards.
In particular, all connections to and from our website are encrypted using Secure Socket Layer (SSL) technology.
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Frequently asked questions
What is Genetic Testing?
Genetic testing sequences DNA to identify any different mutations, differences, or anomalies that may result in the development of hereditary conditions. Prior to ordering a genetic test, we recommend that you educate yourself about the procedure, benefits, limitations and possible consequences of a test result by reading about our tests here. When you’ve educated yourself about the tests and essentially obtained permission for testing, you’ve acquired informed consent. This means you can change your mind about wanting the process even after the test sample has already been collected.
Is Ambrose’s Genetic Testing Covered by Health Insurance?
In most cases, your health insurance or medicare will cover the cost of testing if genetic testing is recommended to you by your doctor. If you are interested in ordering genetic tests, you should contact your insurance company beforehand and ask about coverage.
Does my doctor need to OK this test?
This test can be approved by one of our Telemed Physicians or by your Primary Care Physician. We CAN NOT send any of our patients a kit unless a doctor signs off on it being Medically Necessary.
Can I cancel if I want to?
If for any reason throughout the process, you decide not to move forward with our tests, Ambrose will cancel your request immediately.
References:
1. Tung N, Battelli C, Allen B, et al. Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel. Cancer. January 2015;121(1):25-33. PubMed Abstract.
2. Pal T, Permuth-Wey J, Betts JA, et al. BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases. Cancer. December 2005;104(12):2807-16. PubMed Abstract.
3. Claus EB, Risch N, Thompson WD, et al. The calculation of breast cancer risk for women with a first degree family history of ovarian cancer. Breast Cancer Res Treat. November 1993;28(2):115-20. PubMed Abstract.
4. Risch HA, McLaughlin JR, Cole DE, et al. Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. Am J Hum Genet. March 2001;68(3):700-10. PubMed Abstract.